Browse New and Exciting Opportunities
The Steely Group
http://www.thesteelygroup.com
http://www.thesteelygroup.com
true
Scientist - Cell-Based Assay Development & Execution
Posted: 01/10/2025
2025-01-10
2025-02-24
Employment Type:
Contract
Job Category: Scientific
Job Number: 4219
Job Description
Responsibilities:
- The development and optimization of novel cell-based assays ensure successful implementation and routine execution of these assays to support HTS, lead optimization, and mechanism-of-action studies for promising therapeutic targets
- Design and implement laboratory experiments, generate & interpret data supporting the successful development of new assays and test the biological effects of therapeutic agentsÂ
- Design, implement, and optimize gene-editing workflows in a manner that enables development and evaluation of cell-based functional assays supporting therapeutic target screening or lead optimization studies
- Learn, apply, and incorporate automation solutions during assay development, assay troubleshooting, mechanism-of-action studies, data analysis, and reporting
- Investigate, identify, develop, and optimize new methods/techniques to generate reliable and reproducible data promptly
- Semi-independently plan and implement experiments, adapt readily to changing project needs and develop sophisticated problem-identification and problem resolution skills
- Maintain proficiency with the latest scientific literature and rationale surrounding drug targets and be an active contributor to the interpretation of results in group discussions
- Show excellent collaboration and communication skills as this role requires an ability to work closely with other scientists in the group and across the company
- Adherence to good laboratory conduct, documentation practices, and safety guidelines
- 0+ Years w/ Relevant PhD or equivalent (where applicable) 2+ Years w/ Relevant MS or equivalent 4+ Years w/ Relevant BS or equivalent Advanced and proficient understanding and use of technical principles, theories, and concepts to perform expansive range of work in a role. Basic knowledge of related and adjacent disciplinary areas.
- Ph.D. degree or a master’s degree with 5+ years postgraduate experience in cell and/or molecular biology or closely related field
- Experience working as part of a multi-disciplinary team in a biopharmaceutical setting
- Strong scientific foundation in the understanding and implementation of a wide range of cell-based assays (e.g., TR-FRET, BRET, AlphaLISA, HCS, luminescence and fluorescence-based reporter and/or label-free assays) with experience in the utilization of lab automation across assay development and screening
- Track record of developing, implementing, and performing novel cell-based screening assays in microtiter plates to support early drug discovery research
- Ability to design and implement gene editing (CRISPR knock out/in) workflows enabling the development of targets specific and disease-relevant cell-based assays
- Capacity to identify, evaluate, implement, and become proficient in novel laboratory techniques
- Ability to create and establish priorities, manage work plans, and meet timeline
- A flexible approach with strong interpersonal, communication and problem-solving skills
- Demonstrated initiative, teamwork, collaboration, and passion for developing technical expertise across assay development to routine execution
- Familiarity with software and statistical platforms for the analysis of large data sets (e.g., Screener, Spotfire)
Share This Job:
Related Jobs:
Login to save this search and get notified of similar positions.About Thousand Oaks, CA
Ready to take your career to the next level in the vibrant city of Thousand Oaks, California? Nestled in the heart of Ventura County, this bustling city offers a perfect blend of suburban charm and urban amenities. With a strong job market, top-notch schools, and breathtaking views of the Santa Monica Mountains, Thousand Oaks is an ideal location for professionals seeking growth and fulfillment. Explore job opportunities near iconic sites like the Gardens of the World, catch a show at the Fred Kavli Theatre, or indulge in the local culinary scene featuring dishes from around the world. Join this dynamic community and unlock your potential in Thousand Oaks! Start your job search now to find your perfect fit in this captivating city.