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The Steely Group
http://www.thesteelygroup.com
http://www.thesteelygroup.com
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Scientist, Preformulation
Posted: 03/12/2025
2025-03-12
2025-04-17
Employment Type:
Contract
Job Category: Scientific
Job Number: 4319
Job Description
Our client is seeking an exceptional candidate to contribute to preformulation research in a small, fast-paced and highly collaborative team. This contract position resides within the Formulations Sciences group of Technical Operations working in pre-clinical development.
The candidate will work full time onsite and contribute to the execution of laboratory activities related to the transition of novel small molecule compounds from Discovery into Development in support of the pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments.
Experience in preformulation development and physicochemical characterization is highly desired, however not required.
An ideal candidate would have approximately 0-3 years experience working in pharmaceutical sciences (preformulation, analytical or formulation development).
Responsibilities:
The candidate will work full time onsite and contribute to the execution of laboratory activities related to the transition of novel small molecule compounds from Discovery into Development in support of the pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments.
Experience in preformulation development and physicochemical characterization is highly desired, however not required.
An ideal candidate would have approximately 0-3 years experience working in pharmaceutical sciences (preformulation, analytical or formulation development).
Responsibilities:
- Prepare buffers and common lab solutions
- Execution of analytical experiments with XRPD, DSC, TGA, DVS, optical microscopy and UPLC/HPLC (Empower)
- Screen excipients/formulation vehicles for solubility and stability to optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies
- Perform drug substance and formulation stability studies to ensure optimal formulation design
- Coordinate vehicle/formulation preparations for in vivo studies
- Maintain an accurate, timely, and compliant laboratory notebook
- Minimally a BS degree in chemistry, analytical chemistry, pharmaceutics, chemical engineering or material sciences
- Experience in the Discovery and Development interface [desirable not required]
- Experience working with common excipients and volumetric glassware
- Proficiency with UPLC/HPLC and Empower Software
- Some knowledge of and interest in learning more about small molecule and pre-clinical formulation development
- Ability to effectively prioritize and manage multiple tasks and compounds
- Self-motivated and willing to “learn on the job” and ask for assistance when needed
- At home in a results-driven, highly accountable environment where you can make a clear impact
- A team player, who listens effectively and invites response and discussion
- A collaborator who communicates in an open, clear, complete, timely and consistent manner
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