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Associate Scientist
Job Description
Our client is seeking a highly motivated and detail-oriented Associate Scientist to join the team focused on membrane protein purification and laboratory operations. This role offers an excellent opportunity to contribute to innovative research projects, develop expertise in protein purification technologies, and advance in a collaborative scientific environment. The Associate Scientist will play a key role in executing established protocols, supporting various stages of protein production, and maintaining meticulous records to ensure experimental accuracy and reproducibility. Successful candidates will be eager to learn, thrive in a fast-paced setting, and be committed to scientific excellence.
Key Responsibilities:
- Perform membrane protein purification, including cell lysis and membrane pellet preparation
- Conduct affinity chromatography using anti-FLAG, Strep-Tactin, and Ni-NTA purification systems
- Operate AKTA chromatography systems for protein purification workflows
- Run and analyze SDS-PAGE gels and Western blots
- Perform protein concentration analysis using spectrophotometry and colorimetric assays
- Utilize HPLC methods for protein quality control
- Maintain detailed laboratory documentation and experimental records
- Support inventory management, reagent preparation, and laboratory organization
- Manage storage and tracking of protein inventories
Qualifications:
- Associate’s, Bachelor’s, or Bachelor of Science degree in a scientific discipline
- Minimum of 2 years of laboratory experience in academic or industrial settings
- Hands-on experience with standard molecular biology and biochemistry techniques
- Proficiency with micropipetting, centrifuges, balances, pH meters, and related laboratory equipment
- Strong understanding of sterile techniques and mammalian cell culture practices
- Ability to follow established protocols with a keen attention to detail
- Effective written and verbal communication skills
Preferred Qualifications:
- Experience with membrane protein purification
- Familiarity with AKTA chromatography systems
- Experience culturing mammalian cells
- Knowledge of protein characterization and analytical techniques
Work Location:
Onsite - South San Francisco, California
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