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Sr. Research Scientist, Translational Sciences

Cambridge, MA

Posted: 10/07/2019 Employment Type: Direct Hire Job Category: Clinical: Scientific Job Number: 2446

Our client’ s Translational Sciences Department is looking for an experienced scientist to join their team responsible for the preclinical and translational development of their upcoming clinical stage drug candidates. You will develop the translational strategies for an epigenetic program, such as disease indication selection, PD and patient selection biomarker identification, dose/scheduling strategy, combination strategy, and drug candidate differentiation, etc. If you have successful experience in translational biomarker and IND enabling studies, this is the new role for you. Outstanding track record of scientific achievement is required. Deep understanding of epigenetics is preferred.

How you will spend your day:
  • Lead the preclinical and translational development of your program from candidate nomination to phase I
  • Define translational strategies for disease indication selection, PD and patient selection biomarker identification, dose/scheduling strategy, combination strategy, and drug candidate differentiation, etc.
  • Lead related internal and external collaborations and serve as the point person for CROs and external collaborators
  • Design and conduct MOA studies to gain a deep understanding of drug properties in order to guide clinical develop strategy

A few more key things about you:
  • Ph.D. in biochemistry, cell or molecular biology, pharmacology, medical science, or related fields is required
  • 4+ years of drug development experience in industry is required
  • Experience in IND enabling studies and IND filing with small molecule oncology drugs are required
  • Experience in preclinical and clinical translational biomarker development is required

 

Sam Williams
Clinical Recruiter

Sam brings great enthusiasm and a passion for the life sciences to his role as Clinical Recruiter for The Steely Group. Outgoing and driven with a great sense of humor, Sam connects easily with people and prides himself on his ability to cultivate lasting relationships. He values honesty, communication and empathy in a candidate, and has a genuine interest in helping others achieve their professional goals.

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