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Senior Investigator/AD - Data Science and Bioinformatics

Cambridge, MA

Posted: 04/17/2020 Employment Type: Direct Hire Job Category: Clinical: Biometrics Job Number: 2522

Job Description


We are seeking a highly motivated computational biologist with leading expertise and diverse backgrounds to join our client’ s data science and bioinformatics team. The ideal candidate should have solid scientific, computational and statistic training, and is delivery oriented with a focus on real world impact. The candidate should also be a quick learner, extremely flexible and able to adapt to needs and new scientific advancements.

Principal Duties and Responsibilities:
  • Lead the team effort in computational NGS analysis (RNAseq, DNAseq, single cell sequencing), including identifying fit-for-purpose tools and pipelines, implementing or/and working with vendors to streamline the workflow in suitable computing environment
  • Lead the team effort to identify and bring in new computatinoal capabilities to advance data driven drug discovery and development
  • Contribute to the identification and validation of novel cancer targets leveraging public and proprietary cancer genomics and genetics data, and work closely with target validation teams.
  • Represent data science discipline in drug discovery project team to provide broad range of support and ensure best use of all relevant data impacting project decisions; Summarize and present scientific results with clear conclusions and recommendations.
  • Contribute to the development of innovative data management / integration and information intelligence solutions:
  • Act as bridge between end users and developers to clarify and define system requirement.
  • Provide bioinformatics support to ensure data quality and usability.
  • Maintain expertise in state-of-the-art bioinformatics and cancer genomics methods.
  • Communication:
  • Proactively communicate to supervisor and key stakeholders of activities and status.
  • Generate patent, technical documents, external publications and presentation.
  • Work with external vendors to achieve business goals.
  • Must be able to multi-task.

Qualifications:
  • Ph.D in bioinformatics, computational biology, computer science, or related field, 5+ years of working experience in biopharma industry in the area of oncology or oncogenomics preferred
  • Expertise in computational tools and pipelines for data analysis including but not limited to:
  • NGS data, including RNAseq, WES and WGS, single cell sequencing
  • Diverse types of omics data such as genomic alterations, transcriptome profiling, copy number profiling, as well as data from various proteomics platforms
  • Data from large scale loss / gain of function screening experiments
  • Background in deep learning and AI a plus
  • Solid understanding of statistical analysis principles and expert user of the statistical data analysis tools / packages, such as R/bioconductor, python, matlab, or equivalent
  • Strong computational and engineering skills including database and software development training / experience, ability to independently manipulate large datasets in Unix/Linux environment; experience with AWS preferred
  • Must be a quick learner with strong curiosity, and stay at forefront of technologies in the area of computational biology and genomics
  • Proficiency in common cancer genomics / bioinformatics databases and tools
  • Ability to understand real world problems thoroughly and propose fit-for-purpose solutions to the right question; ability to independently design and perform diverse bioinformatics tasks to answer questions impactful for projects
  • Experience with data visualization as an effective way of presenting and communicating results
  • Experience and training in the area of machine learning
  • Must be a team player and willing to help and ask for help; excellent written and verbal communication skills; excellent interpersonal skills with a proven record of interacting with bench scientists effectively.

Meet Your Recruiter

Tracey Goldthwaite
Senior Vice President

Tracey spearheads the firm’s Commercial practice and focuses on identifying and placing individuals in leadership roles within Global Marketing, Medical Affairs, New Product Planning, and Patient Advocacy and Engagement, to name a few. With 25 years of experience, she also plays a key role in the Clinical Staffing practice, recruiting top talent of all levels for positions in our core areas including Clinical Operations and Development, Regulatory Affairs, Pharmacovigilance and Program Management.

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