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Research Associate - Molecular Biology / Biomarker Development (Contract)

Cambridge, MA

Posted: 06/05/2019 Employment Type: Contract Job Category: Clinical: Scientific Job Number: 2370

Our Client is seeking a highly motivated and enthusiastic Research Associate to join the Biomarker and Companion Diagnostics Group which is responsible for translating preclinical biomarkers into clinical trials.

This is a one-year Contract role and primary responsibilities will be developing and implementing molecular biomarker assays for clinical trial specimens. Excellent communication skills and organization will be required as this position interacts with external vendors, clinical biomarker operations, translational biologists and data scientists. In our Client’ s innovative and fast-paced environment, this position offers the opportunity to acquire new skills and gain broad exposure to new technologies, cancer biomarker discovery, clinical trials and clinical biomarker testing.

Principal Duties and Responsibilities:
  • Developing and implementing a variety biomarker assays, primarily focusing on molecular and genomic-based assays, with some portion of protein based assays.
  • Routine testing of clinical samples utilizing molecular technologies including but not limited to qPCR, Nanostring, ddPCR and NGS for both early phase clinical trials and pre-clinical samples
  • Ability to perform nucleic acid extractions from FFPE blocks and fresh frozen tissues
  • Comfortable with analyzing biomarker data and presenting to project teams
  • Maintenance of laboratory records, protocols, summaries, and technical reports
  • Contribution to laboratory organization and maintenance
  • Contribution to clinical sample related sample and data logistics which includes:
    • Having a clear understanding of the biomarker sample management plan
    • Working with clinical operations to ensure samples are collected and shipped from clinical sites
    • Updating internal biomarker LIMS and database with new sample listings and data
  • 70% lab work, 30% biomarker operations

Requirements / Qualifications:
  • BS/MS with 3+ years of industrial/academic laboratory experience or equivalent
  • Experience in drug discovery, clinical sample testing and clinical trials, especially in oncology is desirable
  • Prior laboratory experience with molecular and genomic based assay technologies such as Nanosting, RT-PCR/ddPCR and NGS is highly preferred
  • Prior experience with flow cytometry, ELISA is a plus.
  • Highly analytical mind, attention to detail, and organization skills are critical
  • Familiarity with keeping an electronic notebook is preferred.
  • Collaborative and proactive attitude with excellent written and oral communication skills
  • Competency in Spotfire, Prism or similar analysis tools is preferred.

Sam Williams
Clinical Recruiter

Sam brings great enthusiasm and a passion for the life sciences to his role as Clinical Recruiter for The Steely Group. Outgoing and driven with a great sense of humor, Sam connects easily with people and prides himself on his ability to cultivate lasting relationships. He values honesty, communication and empathy in a candidate, and has a genuine interest in helping others achieve their professional goals.

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